CVS is closing a staggering 270 stores across the United States in 2025 — a move that has caught customers and industry watchers by surprise. But what’s really driving this sweeping shutdown of locations? Keep reading to uncover the real reason behind these closures and what they mean for communities nationwide.
CVS Store Closures Raise Questions: Bold Plan or Business Trouble?
CVS is set to close a total of 271 stores this year, adding to a sweeping overhaul of its national retail footprint that has been unfolding over the past few years. These store closures in 2025 follow approximately 900 shutdowns between 2022 and 2024.
The company frames the latest wave of closures as a forward-looking strategy. In its February annual report, CVS outlined an “enterprise-wide restructuring plan” aimed at optimizing operations and keeping pace with shifting consumer demands and healthcare trends. The company called the closures a deliberate effort to sharpen service and retail efficiency.
A spokesperson for CVS told Newsweek that this year’s store closures are based on “local population shifts, consumer buying behavior, pharmacy and store density, pharmacy access, and community health data.” CVS maintains this isn’t a reaction to competitive pressures but part of a long-term vision revealed in 2021.
In fact, the company pointed out that despite the closures, access to its services will remain widespread. According to CVS, “85 per cent of Americans will continue to live within 10 miles of a CVS Pharmacy.”
Whether this is indeed a proactive pivot or a signal of deeper challenges remains to be seen — but either way, CVS’s next chapter is already unfolding.
Confirmed CVS Store Closures for 2025
While CVS has yet to publish an official nationwide list of all 2025 store closures, independent data gathered by various news outlets has identified 39 locations that have either already closed or are slated for closure:
Alabama
- 2901 Morgan Rd., Bessemer
- 3303 Clairmont Ave., Birmingham
California
- 499 Haight St., San Francisco
- 1701 K St., Sacramento
Florida
- 13300 E. Colonial Dr., Orlando
- 2201 Edgewater Dr., Orlando
- 3090 S. Monroe St., Tallahassee
Georgia
- 439 Highland Blvd., Atlanta
Illinois
- 401 W. Armitage Ave., Chicago
- 8639 S. Cicero Ave., Chicago
- 2000 Skokie Valley Rd., Highland Park
Indiana
- 9550 Allisonville Rd., Indianapolis
Iowa
- 215 Euclid Ave., Des Moines
- 2420 Lincoln Way, Ames
Maryland
- 34 N. Cannon Ave., Hagerstown (closing June 26th)
- 7235 Wisconsin Ave., Bethesda
- 1000 S. Charles St., Baltimore
Massachusetts
- 55 Summer St., Boston
Michigan
- 27700 Harper Ave., St. Clair Shores
- 28774 Gratiot Ave., Roseville
Missouri
- 2435 Independence Ave., Kansas City
- 4531 Troost Ave., Kansas City
- 9433 Manchester Rd., Saint Louis
New York
- 153 Central Ave., Albany
- 1026 Madison Ave., Albany
- 1241 Lexington Ave., New York
- 1654 Richmond Ave., Staten Island
- 955 Payne Ave., North Tonawanda
North Carolina
- 201 W. 4th St., Winston-Salem
Ohio
- 10825 Kinsman Rd., Cleveland
Pennsylvania
- 125 E. Main St., Plymouth
Texas
- 3890 Phelan Blvd., Beaumont
Virginia
- 10390 Willard Way, Fairfax
Washington, D.C.
- 400 Massachusetts Ave. NW
- 1100 4th St. SW
- 1117 10th St. NW
- 1515 New York Ave. NE
- 4500 Wisconsin Ave. NW
- 7828 Georgia Ave. NW
CVS Balances Store Shutdowns with New Pharmacy Launches
Even as CVS continues its retail consolidation, the company has announced plans to open 30 new pharmacy locations in 2025. Many of these will be pharmacy counters inside select Target stores, allowing CVS to sustain a strong presence across both urban and suburban communities.
However, it’s worth noting that more stores are facing potential shutdown in Arkansas over recent pharmacy legislation in the state. Governor Sarah Huckabee Sanders recently signed a bill restricting pharmacy ownership by Pharmacy Benefit Managers—a move CVS warns could significantly affect its 23 stores in the state.
Source: The Economic Times